2022

Analyzing the Distribution of Cell Shape and Speed in Co-Cultures of Solid-Like Epithelial Cells and Fluid-Like Mesenchymal Cells 

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Faculty Sponsor: Jen Mitchel Abstract: Epithelial cells are typically solid-like (SL), but in the case of injury, development, or cancer these cells can undergo a pseudo-phase transition becoming more fluid-like (FL). During this phase transition, cell shape becomes more elongated with increased variability. Interestingly, in both SL and FL cells, cell shape is defined by … Read more

Probing GNN Enrichment and Ribosome Function

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Faculty Sponsor: Dr. Michael Weir Abstract: The ribosome CAR interaction surface is hypothesized to provide a layer of translation regulation through hydrogen-bonding to the +1 mRNA codon that is next to enter the ribosome A site during translocation. In a previous study, we used molecular dynamics simulations to investigate the codon sequence specificity of this … Read more