Faculty Sponsor: Laverne Melón
Abstract: While excessive alcohol consumption is associated with increased mortality and disease burden, economic costs, and Alcohol Use Disorder (AUD), knowledge of binge drinking history may give insight into behavioral responses to chronic stress. Following a binge drinking period of 14 or 7 days, mice were placed in an elevated plus maze (EPM), or underwent a social interaction or forced test (FST) after a period of withdrawal. Their responses were analyzed by investigating different factors, such as whether they binged on ethanol or water, preference for ethanol over water, stage in the estrus cycle (for females only), and sex. However, some of the mice examined for the social interaction test were given either acamprosate, a pharmacotherapy treatment for AUD, or SGE-516, a synthetic neuroactive steroid.
Jonahs-QAC-Poster-1